Gene name:
Epcam (Tacstd1) ;
Protein name:
Epithelial cell adhesion molecule (Ep-CAM) ;
Alternative:
Protein D5.7A ;Epithelial glycoprotein 314 (EGP314) ;Tumor-associated calcium signal transducer 1 ;
CD:
CD326 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Monomer (By similarity). Interacts with phosphorylated CLDN7.
Function:
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Subcellular Location:
Lateral cell membrane
Single-pass type I membrane protein
Cell junction
tight junction
Co-localizes with CLDN7 at the lateral cell membrane and tight junction.
Protein Attributes:
50:
MAPPKALAFG | LLLAVVTATL | AAAQKDCVCN | NYKLTSRCYE | NENGECQCTS |
100:
YGTQNTVICS | KLASKCLVMK | AEMTHSKSGR | RMKPEGAIQN | NDGLYDPECD |
150:
EQGLFKAKQC | NGTATCWCVN | TAGVRRTDKD | TEITCSERVR | TYWIIIELKH |
200:
KERAQPYNFE | SLHTALQDTF | ASRYMLNPKF | IKSIMYENNV | ITIDLMQNSS |
250:
QKTQDDVDIA | DVAYYFEKDV | KGESLFHSSK | SMDLRVNGEL | LDLDPGQTLI |
300:
YYVDEKAPEF | SMQGLTAGII | AVIVVVVLAV | IAGIVVLVIS | TRKRSAKYEK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
Chicken
Polyclonal Antibody for Rat Ep-CAM
Polyclonal Antibody for Rat Ep-CAM
Polyclonal Antibody for Rat Ep-CAM
Polyclonal Antibody for Rat Ep-CAM
Polyclonal Antibody for Rat Ep-CAM
Monoclonal Antibody for Rat Ep-CAM
Monoclonal Antibody for Rat Ep-CAM
Monoclonal Antibody for Rat Ep-CAM
Monoclonal Antibody for Rat Ep-CAM
Monoclonal Antibody for Rat Ep-CAM
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
BDIX .
tissue :
Colon carcinoma .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Lung .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION INTERACTION WITH CLDN7