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Index > Protein center > Epcam(Gene name) > Rat
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  • Epcam (Gene name),
  • Epithelial cell adhesion molecule (Protein name ),  EPCAM_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Epcam(Tacstd1);
    Protein name:
    Epithelial cell adhesion molecule(Ep-CAM);
    Alternative:
    Protein D5.7A;Epithelial glycoprotein 314(EGP314);Tumor-associated calcium signal transducer 1;
    CD:
    CD326;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Monomer (By similarity). Interacts with phosphorylated CLDN7.
    Function:
    May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
    Subcellular Location:
    Lateral cell membrane Single-pass type I membrane protein Cell junction tight junction Co-localizes with CLDN7 at the lateral cell membrane and tight junction.
    Protein Attributes:
    Sequence length:
    315
    Sequence:
    50:
    MAPPKALAFG | LLLAVVTATL | AAAQKDCVCN | NYKLTSRCYE | NENGECQCTS | 
    100:
    YGTQNTVICS | KLASKCLVMK | AEMTHSKSGR | RMKPEGAIQN | NDGLYDPECD | 
    150:
    EQGLFKAKQC | NGTATCWCVN | TAGVRRTDKD | TEITCSERVR | TYWIIIELKH | 
    200:
    KERAQPYNFE | SLHTALQDTF | ASRYMLNPKF | IKSIMYENNV | ITIDLMQNSS | 
    250:
    QKTQDDVDIA | DVAYYFEKDV | KGESLFHSSK | SMDLRVNGEL | LDLDPGQTLI | 
    300:
    YYVDEKAPEF | SMQGLTAGII | AVIVVVVLAV | IAGIVVLVIS | TRKRSAKYEK | 
    315:
    AEIKEMGEIH | RELNA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Ep-CAM
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    E1283h
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    ELISA Kit for Rat Ep-CAM
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    E1283m
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    ELISA Kit for Rat Ep-CAM
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    E1283r
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    ELISA Kit for Rat Ep-CAM
    Cat.:
    E1283b
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    ELISA Kit for Rat Ep-CAM
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    E1283c
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    96T
    CLIA Kit for Rat Ep-CAM
    Cat.:
    U1283b
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    96T
    CLIA Kit for Rat Ep-CAM
    Cat.:
    U1283c
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    96T
    CLIA Kit for Rat Ep-CAM
    Cat.:
    U1283r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Ep-CAM
    Cat.:
    U1283h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Rat Ep-CAM
    Cat.:
    U1283m
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    Packing:
    96T
    Polyclonal Antibody for Rat Ep-CAM
    Polyclonal Antibody for Rat Ep-CAM
    Cat.:
    P1283Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Ep-CAM
    Cat.:
    P1283Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Ep-CAM
    Polyclonal Antibody for Rat Ep-CAM
    Cat.:
    P1283Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Ep-CAM
    Monoclonal Antibody for Rat Ep-CAM
    Monoclonal Antibody for Rat Ep-CAM
    Monoclonal Antibody for Rat Ep-CAM
    Monoclonal Antibody for Rat Ep-CAM
    Protein for Rat Ep-CAM
    Protein for Rat Ep-CAM
    Protein for Rat Ep-CAM
    Protein for Rat Ep-CAM
    Protein for Rat Ep-CAM

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    References
    1. 1.
      "Metastasis-association of the rat ortholog of the human epithelial glycoprotein antigen EGP314."
      Wuerfel J. , Roesel M. , Seiter S. , Claas C. , Herlevsen M. , Weth R. , Zoeller M.
      Oncogene18:2323-2334(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BDIX.
      tissue: Colon carcinoma.
    2. 2.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    4. 4.
      "The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7."
      Ladwein M. , Pape U.F. , Schmidt D.S. , Schnoelzer M. , Fiedler S. , Langbein L. , Franke W.W. , Moldenhauer G. , Zoeller M.
      Exp. Cell Res.309:345-357(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION INTERACTION WITH CLDN7
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